Database Commons a catalog of biological databases

Database Commons - RNAdb

RNAdb

Citations: 290

z-index 10.71

Short name RNAdb
Full name
Description A database of mammalian noncoding RNAs.
URL http://research.imb.uq.edu.au/rnadb/
Year founded 2004
Last update & version 2012-06-01    2.0
Availability Free to all users
University/Institution hosted University of Queensland
Address Brisbane, Queensland 4072, Australia
City Brisbane
Province/State
Country/Region Australia
Contact name John S. Mattick
Contact email j.mattick@imb.uq.edu.au
Data type(s)
Major organism(s)
Keyword(s)
  • non-coding RNA
Publication(s)
  • RNAdb 2.0--an expanded database of mammalian non-coding RNAs. [PMID: 17145715]

    Ken C Pang, Stuart Stephen, Marcel E Dinger, Pär G Engström, Boris Lenhard, John S Mattick
    Nucleic acids research 2007:35(Database issue)
    137 Citations (Google Scholar as of 2016-01-20)

    Abstract: RNAdb is a comprehensive database of mammalian non-protein-coding RNAs (ncRNAs). There is increasing recognition that ncRNAs play important regulatory roles in multicellular organisms, and there is an expanding rate of discovery of novel ncRNAs as well as an increasing allocation of function. In this update to RNAdb, we provide nucleotide sequences and annotations for tens of thousands of non-housekeeping ncRNAs, including a wide range of mammalian microRNAs, small nucleolar RNAs and larger mRNA-like ncRNAs. Some of these have documented functions and/or expression patterns, but the majority remain of unclear significance, and include PIWI-interacting RNAs, ncRNAs identified from the latest rounds of large-scale cDNA sequencing projects, putative antisense transcripts, as well as ncRNAs predicted on the basis of structural features and alignments. Improvements to the database comprise not only new and updated ncRNA datasets, but also provision of microarray-based expression data and closer interface with more specialized ncRNA resources such as miRBase and snoRNA-LBME-db. To access RNAdb, visit http://research.imb.uq.edu.au/RNAdb.

  • RNAdb--a comprehensive mammalian noncoding RNA database. [PMID: 15608161]

    Ken C Pang, Stuart Stephen, Pär G Engström, Khairina Tajul-Arifin, Weisan Chen, Claes Wahlestedt, Boris Lenhard, Yoshihide Hayashizaki, John S Mattick
    Nucleic acids research 2005:33(Database issue)
    153 Citations (Google Scholar as of 2016-01-20)

    Abstract: In recent years, there have been increasing numbers of transcripts identified that do not encode proteins, many of which are developmentally regulated and appear to have regulatory functions. Here, we describe the construction of a comprehensive mammalian noncoding RNA database (RNAdb) which contains over 800 unique experimentally studied non-coding RNAs (ncRNAs), including many associated with diseases and/or developmental processes. The database is available at http://research.imb.uq.edu.au/RNAdb and is searchable by many criteria. It includes microRNAs and snoRNAs, but not infrastructural RNAs, such as rRNAs and tRNAs, which are catalogued elsewhere. The database also includes over 1100 putative antisense ncRNAs and almost 20,000 putative ncRNAs identified in high-quality murine and human cDNA libraries, with more to be added in the near future. Many of these RNAs are large, and many are spliced, some alternatively. The database will be useful as a foundation for the emerging field of RNomics and the characterization of the roles of ncRNAs in mammalian gene expression and regulation.

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200 OK2016-01-29
200 OK2016-01-27
200 OK2016-01-25
200 OK2016-01-24
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200 OK2016-01-17
200 OK2016-01-15
200 OK2016-01-13
200 OK2016-01-11
200 OK2016-01-10
200 OK2016-01-08
200 OK2016-01-06
200 OK2016-01-04

Tags

RNA
Homo sapiens Mus musculus
non-coding RNA

Record metadata

  • Created on: 2015-07-11
  • Curated by:
    • Lin Xia [2016-04-01]
    • Mengwei Li [2016-02-07]
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