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Database Commons - HCAD

HCAD

Citations: 10

z-index 0.00

Short name HCAD
Full name Human Chromosome Aberration Database
Description The Human Chromosome Aberration Database (HCAD) shows that the statistical analysis of this textual information and its combination with genomic data can identify genes directly involved in DNA rearrangements.
URL http://www.pdg.cnb.uam.es/UniPub/HCAD/
Year founded 2004
Last update & version     
Availability Not Available
University/Institution hosted Spanish National Centre for Biotechnology
Address Campus de la UAM, Cantoblanco, Madrid 28049, Spain
City Madrid
Province/State
Country/Region Spain
Contact name Robert Hoffmann
Contact email hoffmann@cnb.uam.es
Data type(s)
Major organism(s)
Keyword(s)
  • DNA rearrangement
Publication(s)
  • HCAD, closing the gap between breakpoints and genes. [PMID: 15608250]

    Robert Hoffmann, Joaquin Dopazo, Juan C Cigudosa, Alfonso Valencia
    Nucleic acids research 2005:33(Database issue)
    10 Citations (Google Scholar as of 2016-02-29)

    Abstract: Recurrent chromosome aberrations are an important resource when associating human pathologies to specific genes. However, for technical reasons a large number of chromosome breakpoints are defined only at the level of cytobands and many of the genes involved remain unidentified. We developed a web-based information system that mines the scientific literature and generates textual and comprehensive information on all human breakpoints. We show that the statistical analysis of this textual information and its combination with genomic data can identify genes directly involved in DNA rearrangements. The Human Chromosome Aberration Database (HCAD) is publicly accessible at http://www.pdg.cnb.uam.es/UniPub/HCAD/.

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Tags

DNA
Homo sapiens
DNA rearrangement

Record metadata

  • Created on: 2015-07-14
  • Curated by:
    • Chunlei Yu [2016-03-31]
    • Chunlei Yu [2015-11-19]
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