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Database Commons - HLungDB

HLungDB

Citations: 48

z-index 0.12

Short name HLungDB
Full name Human Lung Cancer Database
Description The human lung cancer database (HLungDB) is a database with the integration of the lung cancer-related genes, proteins and miRNAs together with the corresponding clinical information.
URL http://www.megabionet.org/bio/hlung
Year founded 2010
Last update & version 2009-11-09    v1.0
Availability Not Available
University/Institution hosted East China Normal University
Address Shanghai 200241, China
City Shanghai
Province/State
Country/Region China
Contact name Tieliu Shi
Contact email tlshi@sibs.ac.cn
Data type(s)
Major organism(s)
Keyword(s)
  • lung cancer
Publication(s)
  • HLungDB: an integrated database of human lung cancer research. [PMID: 19900972]

    Lishan Wang, Yuanyuan Xiong, Yihua Sun, Zhaoyuan Fang, Li Li, Hongbin Ji, Tieliu Shi
    Nucleic acids research 2010:38(Database issue)
    48 Citations (Google Scholar as of 2016-04-08)

    Abstract: The human lung cancer database (HLungDB) is a database with the integration of the lung cancer-related genes, proteins and miRNAs together with the corresponding clinical information. The main purpose of this platform is to establish a network of lung cancer-related molecules and to facilitate the mechanistic study of lung carcinogenesis. The entries describing the relationships between molecules and human lung cancer in the current release were extracted manually from literatures. Currently, we have collected 2585 genes and 212 miRNA with the experimental evidences involved in the different stages of lung carcinogenesis through text mining. Furthermore, we have incorporated the results from analysis of transcription factor-binding motifs, the promoters and the SNP sites for each gene. Since epigenetic alterations also play an important role in lung carcinogenesis, genes with epigenetic regulation were also included. We hope HLungDB will enrich our knowledge about lung cancer biology and eventually lead to the development of novel therapeutic strategies. HLungDB can be freely accessed at http://www.megabionet.org/bio/hlung.

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Tags

DNA
Homo sapiens
lung cancer

Record metadata

  • Created on: 2015-07-16
  • Curated by:
    • Lina Ma [2016-04-08]
    • Chunlei Yu [2016-03-31]
    • Chunlei Yu [2015-11-19]
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