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Database Commons - HUMHOT

HUMHOT

Citations: 5

z-index 0.00

Short name HUMHOT
Full name Human Meiotic Recombination Hot Spots
Description HUMHOT is a web-based database of Human Meiotic Recombination Hot Spots.
URL http://www.jncasr.ac.in/humhot
Year founded
Last update & version 2006-01-01    v1.0
Availability Not Available
University/Institution hosted Indian Institute of Science
Address Bangalore 560012, India
City Bangalore
Province/State
Country/Region India
Contact name M. R. S. Rao
Contact email mrsrao@jncasr.ac.in
Data type(s)
Major organism(s)
Keyword(s)
  • meiotic recombination
Publication(s)
  • HUMHOT: a database of human meiotic recombination hot spots. [PMID: 16381857]

    K T Nishant, Chetan Kumar, M R S Rao
    Nucleic acids research 2006:34(Database issue)
    5 Citations (Google Scholar as of 2016-04-28)

    Abstract: Meiotic recombination occurs preferentially at certain regions in the genome referred to as hot spots. The number of hot spots known in humans has increased manifold in recent years. The identification of these hot spots in humans is of great interest to population and medical geneticists since they influence the structure of Linkage Disequilibrium and Haplotype blocks in human populations, whose patterns have applications in mapping disease genes. HUMHOT is a web-based database of Human Meiotic Recombination Hot Spots. The database comprises DNA sequences corresponding to the hot spot regions from the literature that have been mapped to a high resolution (<4 kb) in humans. It also provides flanking sequence information for the hot spot region along with references describing the hot spot. The database can be queried based on hot spot identity, chromosome position or by homology to user-defined sequences. It is also updated with new hot spot sequences as they are discovered and provides hyperlinks to commonly used tools for estimating recombination rates, performing genetic analysis and new advances in our understanding of meiotic hot spots. Public access to the HUMHOT database is available at http://www.jncasr.ac.in/humhot.

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Tags

DNA
Homo sapiens
meiotic recombination

Record metadata

  • Created on: 2015-07-17
  • Curated by:
    • Chunlei Yu [2016-03-31]
    • Mengwei Li [2016-02-20]
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