Database Commons a catalog of biological databases

Database Commons - TBDB

TBDB

Citations: 154

z-index 8.73

Short name TBDB
Full name Tuberculosis Database
Description TB database is an integrated platform for tuberculosis research.
URL http://www.tbdb.org/
Year founded 2007
Last update & version 2014-02-01    v1.0
Availability Free to all users
University/Institution hosted Stanford University
Address Department of Biochemistry, Stanford University, CA 94305, USA
City Stanford
Province/State CA
Country/Region United States
Contact name T. B. K. Reddy
Contact email tbreddy@stanford.edu
Data type(s)
Major organism(s)
Keyword(s)
  • tuberculosis
Publication(s)
  • TB database: an integrated platform for tuberculosis research. [PMID: 18835847]

    T B K Reddy, Robert Riley, Farrell Wymore, Phillip Montgomery, Dave DeCaprio, Reinhard Engels, Marcel Gellesch, Jeremy Hubble, Dennis Jen, Heng Jin, Michael Koehrsen, Lisa Larson, Maria Mao, Michael Nitzberg, Peter Sisk, Christian Stolte, Brian Weiner, Jared White, Zachariah K Zachariah, Gavin Sherlock, James E Galagan, Catherine A Ball, Gary K Schoolnik
    Nucleic acids research 2009:37(Database issue)
    154 Citations (Google Scholar as of 2016-01-22)

    Abstract: The effective control of tuberculosis (TB) has been thwarted by the need for prolonged, complex and potentially toxic drug regimens, by reliance on an inefficient vaccine and by the absence of biomarkers of clinical status. The promise of the genomics era for TB control is substantial, but has been hindered by the lack of a central repository that collects and integrates genomic and experimental data about this organism in a way that can be readily accessed and analyzed. The Tuberculosis Database (TBDB) is an integrated database providing access to TB genomic data and resources, relevant to the discovery and development of TB drugs, vaccines and biomarkers. The current release of TBDB houses genome sequence data and annotations for 28 different Mycobacterium tuberculosis strains and related bacteria. TBDB stores pre- and post-publication gene-expression data from M. tuberculosis and its close relatives. TBDB currently hosts data for nearly 1500 public tuberculosis microarrays and 260 arrays for Streptomyces. In addition, TBDB provides access to a suite of comparative genomics and microarray analysis software. By bringing together M. tuberculosis genome annotation and gene-expression data with a suite of analysis tools, TBDB (http://www.tbdb.org/) provides a unique discovery platform for TB research.

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Tags

Disease DNA Drug and Chemical Compound
Mycobacterium tuberculosis
tuberculosis

Record metadata

  • Created on: 2015-07-26
  • Curated by:
    • Guangyu Wang [2016-04-01]
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