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Database Commons - PIG

PIG

Citations: 55

z-index 1.16

Short name PIG
Full name Pathogen Interaction Gateway
Description To facilitate the study of host–pathogen PPIs, we have collected and integrated host–pathogen PPI (HP–PPI) data from a number of public resources to create the Pathogen Interaction Gateway (PIG).
URL http://pig.vbi.vt.edu/
Year founded 2008
Last update & version 2009-01-01    v1.0
Availability Not Available
University/Institution hosted Virginia Bioinformatics Institute
Address Virginia Bioinformatics Institute, Blacksburg, VA 24061, USA
City Blacksburg
Province/State VA
Country/Region United States
Contact name Bruno W. Sobral
Contact email sobral@vt.edu
Data type(s)
Major organism(s)
Keyword(s)
  • host–pathogen PPI
Publication(s)
  • PIG--the pathogen interaction gateway. [PMID: 18984614]

    Tim Driscoll, Matthew D Dyer, T M Murali, Bruno W Sobral
    Nucleic acids research 2009:37(Database issue)
    55 Citations (Google Scholar as of 2016-01-25)

    Abstract: Protein-protein interactions (PPIs) play a vital role in initiating infection in a number of pathogens. Identifying which interactions allow a pathogen to infect its host can help us to understand methods of pathogenesis and provide potential targets for therapeutics. Public resources for studying host-pathogen systems, in particular PPIs, are scarce. To facilitate the study of host-pathogen PPIs, we have collected and integrated host-pathogen PPI (HP-PPI) data from a number of public resources to create the Pathogen Interaction Gateway (PIG). PIG provides a text based search and a BLAST interface for searching the HP-PPI data. Each entry in PIG includes information such as the functional annotations and the domains present in the interacting proteins. PIG provides links to external databases to allow for easy navigation among the various websites. Additionally, PIG includes a tool for visualizing a single HP-PPI network or two HP-PPI networks. PIG can be accessed at http://pig.vbi.vt.edu.

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Tags

Disease Interaction and Network
Aedes aegypti Anopheles gambiae Caenorhabditis elegans Danio rerio Homo sapiens Ixodes scapularis Mus musculus Rattus norvegicus
host–pathogen PPI

Record metadata

  • Created on: 2015-07-27
  • Curated by:
    • Shixiang Sun [2016-03-25]
    • Shixiang Sun [2015-11-21]
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