Database Commons a catalog of biological databases

Database Commons - MDPD

MDPD

Citations: 15

z-index 0.73

Short name MDPD
Full name Mutation Database for Parkinson's Disease
Description MDPD is an integrated genetic information resource for Parkinson's disease.
URL http://datam.i2r.a-star.edu.sg/mdpd/
Year founded 2009
Last update & version 2008-10-23    
Availability Free to all users
University/Institution hosted Singapore General Hospital
Address Singapore
City singapore
Province/State
Country/Region Singapore
Contact name Suisheng Tang
Contact email suisheng@i2r.a-star.edu.sg
Data type(s)
Major organism(s)
Keyword(s)
  • mutation
Publication(s)
  • MDPD: an integrated genetic information resource for Parkinson's disease. [PMID: 18948286]

    Suisheng Tang, Zhuo Zhang, Gopalakrishnan Kavitha, Eng-King Tan, See Kiong Ng
    Nucleic acids research 2009:37(Database issue)
    15 Citations (Google Scholar as of 2016-01-27)

    Abstract: Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting millions of people. Both environmental and genetic factors play important roles in its causation and development. Genetic analysis has shown that over 100 genes are correlated with the etiology and pathology of PD. However, accessing genetic information in a consistent and fruitful way is not an easy task. The Mutation Database for Parkinson's Disease (MDPD) is designed to fulfill the need for information integration so that users can easily retrieve, inspect and enhance their knowledge on PD. The database contains 2391 entries on 202 genes extracted from 576 publications and manually examined by biomedical researchers. Each genetic substitution and the resulting impact are clearly labelled and linked to its primary reference. Every reported gene has a summary page that provides information on the variation impact, mutation type, the studied population, mutation position and reference collection. In addition, MDPD provides a unique functionality for users to compare the differences on the type of mutations among ethnic groups. As such, we hope that MDPD will serve as a valuable tool to bridge the gap between genetic analysis and clinical practice. MDPD is publicly accessible at http://datam.i2r.a-star.edu.sg/mdpd/.

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Tags

Disease DNA
Homo sapiens
mutation

Record metadata

  • Created on: 2015-07-27
  • Curated by:
    • Lin Liu [2016-03-26]
    • Mengwei Li [2016-02-20]
    • Li Yang [2015-11-24]
Stats