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Database Commons - D-HaploDB

D-HaploDB

Citations: 9

z-index 0.24

Short name D-HaploDB
Full name The Definitive Haplotype Database
Description D-HaploDB is a web-accessible resource of genome-wide definitive haplotypes determined from a collection of Japanese complete hydatidiform moles (CHMs), each of which carries a genome derived from a single sperm.
URL http://orca.gen.kyushu-u.ac.jp
Year founded 2007
Last update & version 2014-04-24    v4.1
Availability Not Available
University/Institution hosted Kyushu University
Address Fukuoka 812-8582, Japan
City Fukuoka
Province/State
Country/Region Japan
Contact name Kenshi Hayashi
Contact email khayashi@gen.kyushu-u.ac.jp
Data type(s)
Major organism(s)
Keyword(s)
  • genotype
  • Haplotype
  • hydatidiform moles (CHMs)
  • SNP
Publication(s)
  • D-HaploDB: a database of definitive haplotypes determined by genotyping complete hydatidiform mole samples. [PMID: 17166862]

    Koichiro Higasa, Katsuyuki Miyatake, Yoji Kukita, Tomoko Tahira, Kenshi Hayashi
    Nucleic acids research 2007:35(Database issue)
    9 Citations (Google Scholar as of 2016-05-03)

    Abstract: The Definitive Haplotype Database (D-HaploDB) is a web-accessible resource of genome-wide definitive haplotypes determined from a collection of Japanese complete hydatidiform moles (CHMs), each of which carries a genome derived from a single sperm. Currently, the database contains genotypes for 281 439 common SNPs from 74 CHMs which were determined by a high-throughput array-based oligonucleotide hybridization technique. The database also presents maps of haplotype blocks and linkage disequilibrium bins together with tagSNPs that might prove useful for association studies of disease genes. Cryptic relatedness among the samples in this study is unlikely, because the formation of a CHM is a maternal event of rare sporadic occurrence, and its genotype is that of the incoming sperm. This is demonstrated by the absence of long extended shared haplotypes (ESHs). The D-HaploDB is freely accessible via the Internet at http://orca.gen.kyushu-u.ac.jp.

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Tags

DNA
Homo sapiens
genotype Haplotype hydatidiform moles (CHMs) SNP

Record metadata

  • Created on: 2015-08-10
  • Curated by:
    • Lina Ma [2016-04-08]
    • Lina Ma [2016-04-07]
    • Jian Sang [2016-04-04]
    • Lina Ma [2016-03-31]
    • Lina Ma [2015-12-31]
    • Jian Sang [2015-11-24]
Stats