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Database Commons - SGD


Citations: 772

z-index 128.67

Short name SGD
Full name Saccharomyces Genome Database
Description The Saccharomyces Genome Database is the community resource for genomic,gene and protein information about the budding yeast Saccharomyces cerevisiae,containing a variety of functional information about each yeast gene and gene product.
Year founded 2012
Last update & version 2016-03-27    v3.0
Availability Free to all users
University/Institution hosted Stanford University
Address Stanford,CA 94305,USA
City Stanford
Province/State CA
Country/Region United States
Contact name J. Michael Cherry
Contact email
Data type(s)
Major organism(s)
  • gene information
  • genomic information
  • protein information
  • Curated protein information in the Saccharomyces genome database. [PMID: 28365727]

    Sage T Hellerstedt, Robert S Nash, Shuai Weng, Kelley M Paskov, Edith D Wong, Kalpana Karra, Stacia R Engel, J Michael Cherry
    Database : the journal of biological databases and curation 2017:2017(1)
    0 Citations (Google Scholar as of 2017-04-06)

    Abstract: Due to recent advancements in the production of experimental proteomic data, the Saccharomyces genome database (SGD; ) has been expanding our protein curation activities to make new data types available to our users. Because of broad interest in post-translational modifications (PTM) and their importance to protein function and regulation, we have recently started incorporating expertly curated PTM information on individual protein pages. Here we also present the inclusion of new abundance and protein half-life data obtained from high-throughput proteome studies. These new data types have been included with the aim to facilitate cellular biology research. :

  • Outreach and online training services at the Saccharomyces Genome Database. [PMID: 28365719]

    Kevin A MacPherson, Barry Starr, Edith D Wong, Kyla S Dalusag, Sage T Hellerstedt, Olivia W Lang, Robert S Nash, Marek S Skrzypek, Stacia R Engel, J Michael Cherry
    Database : the journal of biological databases and curation 2017:2017(1)
    0 Citations (Google Scholar as of 2017-04-06)

    Abstract: The Saccharomyces Genome Database (SGD; ), the primary genetics and genomics resource for the budding yeast S. cerevisiae , provides free public access to expertly curated information about the yeast genome and its gene products. As the central hub for the yeast research community, SGD engages in a variety of social outreach efforts to inform our users about new developments, promote collaboration, increase public awareness of the importance of yeast to biomedical research, and facilitate scientific discovery. Here we describe these various outreach methods, from networking at scientific conferences to the use of online media such as blog posts and webinars, and include our perspectives on the benefits provided by outreach activities for model organism databases.

  • Integration of new alternative reference strain genome sequences into the Saccharomyces genome database. [PMID: 27252399]

    Giltae Song, Rama Balakrishnan, Gail Binkley, Maria C Costanzo, Kyla Dalusag, Janos Demeter, Stacia Engel, Sage T Hellerstedt, Kalpana Karra, Benjamin C Hitz, Robert S Nash, Kelley Paskov, Travis Sheppard, Marek Skrzypek, Shuai Weng, Edith Wong, J Michael Cherry
    Database : the journal of biological databases and curation 2016:2016
    3 Citations (Google Scholar as of 2017-04-06)

    Abstract: The Saccharomyces Genome Database (SGD; is the authoritative community resource for the Saccharomyces cerevisiae reference genome sequence and its annotation. To provide a wider scope of genetic and phenotypic variation in yeast, the genome sequences and their corresponding annotations from 11 alternative S. cerevisiae reference strains have been integrated into SGD. Genomic and protein sequence information for genes from these strains are now available on the Sequence and Protein tab of the corresponding Locus Summary pages. We illustrate how these genome sequences can be utilized to aid our understanding of strain-specific functional and phenotypic differences.Database URL: © The Author(s) 2016. Published by Oxford University Press.

  • From one to many: expanding the Saccharomyces cerevisiae reference genome panel. [PMID: 26989152]

    Stacia R Engel, Shuai Weng, Gail Binkley, Kelley Paskov, Giltae Song, J Michael Cherry
    Database : the journal of biological databases and curation 2016:2016
    3 Citations (Google Scholar as of 2017-04-06)

    Abstract: In recent years, thousands of Saccharomyces cerevisiae genomes have been sequenced to varying degrees of completion. The Saccharomyces Genome Database (SGD) has long been the keeper of the original eukaryotic reference genome sequence, which was derived primarily from S. cerevisiae strain S288C. Because new technologies are pushing S. cerevisiae annotation past the limits of any system based exclusively on a single reference sequence, SGD is actively working to expand the original S. cerevisiae systematic reference sequence from a single genome to a multi-genome reference panel. We first commissioned the sequencing of additional genomes and their automated analysis using the AGAPE pipeline. Here we describe our curation strategy to produce manually reviewed high-quality genome annotations in order to elevate 11 of these additional genomes to Reference status. Database URL: © The Author(s) 2016. Published by Oxford University Press.

  • The Saccharomyces Genome Database Variant Viewer. [PMID: 26578556]

    Travis K Sheppard, Benjamin C Hitz, Stacia R Engel, Giltae Song, Rama Balakrishnan, Gail Binkley, Maria C Costanzo, Kyla S Dalusag, Janos Demeter, Sage T Hellerstedt, Kalpana Karra, Robert S Nash, Kelley M Paskov, Marek S Skrzypek, Shuai Weng, Edith D Wong, J Michael Cherry
    Nucleic acids research 2016:44(D1)
    9 Citations (Google Scholar as of 2017-04-06)

    Abstract: The Saccharomyces Genome Database (SGD; is the authoritative community resource for the Saccharomyces cerevisiae reference genome sequence and its annotation. In recent years, we have moved toward increased representation of sequence variation and allelic differences within S. cerevisiae. The publication of numerous additional genomes has motivated the creation of new tools for their annotation and analysis. Here we present the Variant Viewer: a dynamic open-source web application for the visualization of genomic and proteomic differences. Multiple sequence alignments have been constructed across high quality genome sequences from 11 different S. cerevisiae strains and stored in the SGD. The alignments and summaries are encoded in JSON and used to create a two-tiered dynamic view of the budding yeast pan-genome, available at © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  • Saccharomyces genome database provides new regulation data. [PMID: 24265222]

    Maria C Costanzo, Stacia R Engel, Edith D Wong, Paul Lloyd, Kalpana Karra, Esther T Chan, Shuai Weng, Kelley M Paskov, Greg R Roe, Gail Binkley, Benjamin C Hitz, J Michael Cherry
    Nucleic acids research 2014:42(Database issue)
    50 Citations (Google Scholar as of 2017-04-06)

    Abstract: The Saccharomyces Genome Database (SGD; is the community resource for genomic, gene and protein information about the budding yeast Saccharomyces cerevisiae, containing a variety of functional information about each yeast gene and gene product. We have recently added regulatory information to SGD and present it on a new tabbed section of the Locus Summary entitled 'Regulation'. We are compiling transcriptional regulator-target gene relationships, which are curated from the literature at SGD or imported, with permission, from the YEASTRACT database. For nearly every S. cerevisiae gene, the Regulation page displays a table of annotations showing the regulators of that gene, and a graphical visualization of its regulatory network. For genes whose products act as transcription factors, the Regulation page also shows a table of their target genes, accompanied by a Gene Ontology enrichment analysis of the biological processes in which those genes participate. We additionally synthesize information from the literature for each transcription factor in a free-text Regulation Summary, and provide other information relevant to its regulatory function, such as DNA binding site motifs and protein domains. All of the regulation data are available for querying, analysis and download via YeastMine, the InterMine-based data warehouse system in use at SGD.

  • Saccharomyces Genome Database: the genomics resource of budding yeast. [PMID: 22110037]

    J Michael Cherry, Eurie L Hong, Craig Amundsen, Rama Balakrishnan, Gail Binkley, Esther T Chan, Karen R Christie, Maria C Costanzo, Selina S Dwight, Stacia R Engel, Dianna G Fisk, Jodi E Hirschman, Benjamin C Hitz, Kalpana Karra, Cynthia J Krieger, Stuart R Miyasato, Rob S Nash, Julie Park, Marek S Skrzypek, Matt Simison, Shuai Weng, Edith D Wong
    Nucleic acids research 2012:40(Database issue)
    707 Citations (Google Scholar as of 2017-04-06)

    Abstract: The Saccharomyces Genome Database (SGD, is the community resource for the budding yeast Saccharomyces cerevisiae. The SGD project provides the highest-quality manually curated information from peer-reviewed literature. The experimental results reported in the literature are extracted and integrated within a well-developed database. These data are combined with quality high-throughput results and provided through Locus Summary pages, a powerful query engine and rich genome browser. The acquisition, integration and retrieval of these data allow SGD to facilitate experimental design and analysis by providing an encyclopedia of the yeast genome, its chromosomal features, their functions and interactions. Public access to these data is provided to researchers and educators via web pages designed for optimal ease of use.

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Rate of accessibility:
HTTP status codeDate requested
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200 OK2018-09-28
200 OK2018-09-25
200 OK2018-09-21
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200 OK2018-09-11
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200 OK2018-09-04
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200 OK2018-08-28
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200 OK2018-08-21
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200 OK2018-07-31
200 OK2018-07-27
200 OK2018-07-24
200 OK2018-07-20
200 OK2018-07-17
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200 OK2018-07-10
200 OK2018-07-06
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200 OK2018-06-29
-1 Failed2018-06-26
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200 OK2018-04-27
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200 OK2018-04-20
200 OK2018-04-17
200 OK2018-04-13
200 OK2018-04-10
200 OK2018-04-06
200 OK2018-04-03
200 OK2018-02-27
200 OK2018-02-23
200 OK2018-02-20
200 OK2018-02-16
200 OK2018-02-13
200 OK2018-02-09
200 OK2018-02-06
200 OK2018-02-02
200 OK2018-01-30
200 OK2018-01-26
200 OK2018-01-23
200 OK2018-01-19
200 OK2018-01-16
200 OK2018-01-12
200 OK2018-01-09
200 OK2018-01-05
200 OK2018-01-02
200 OK2017-12-29
200 OK2017-12-26
200 OK2017-12-22
200 OK2017-12-19
200 OK2017-12-15
200 OK2017-12-12
200 OK2017-12-08
200 OK2017-12-05
200 OK2017-12-01
200 OK2017-11-28
200 OK2017-11-24
200 OK2017-11-21
200 OK2017-11-17
200 OK2017-11-14
200 OK2017-11-10
200 OK2017-11-07
200 OK2017-11-03
200 OK2017-10-31
200 OK2017-10-27
200 OK2017-10-24
200 OK2017-10-20
200 OK2017-10-17
200 OK2017-10-13
200 OK2017-10-10
200 OK2017-10-06
200 OK2017-10-03
200 OK2017-09-29
200 OK2017-09-26
200 OK2017-09-22
200 OK2017-09-19
200 OK2017-09-15
200 OK2017-09-12
200 OK2017-09-08
200 OK2017-09-05
200 OK2017-09-01
200 OK2017-08-29
200 OK2017-08-25
200 OK2017-08-22
200 OK2017-08-18
200 OK2017-08-15
200 OK2017-08-11
200 OK2017-08-08
200 OK2017-08-04
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200 OK2017-07-28
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200 OK2017-07-18
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200 OK2017-07-04
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200 OK2017-06-13
200 OK2017-06-09
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200 OK2017-06-02
200 OK2017-05-30
200 OK2017-05-26
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200 OK2017-05-19
200 OK2017-05-16
200 OK2017-05-12
200 OK2017-05-09
200 OK2017-05-05
200 OK2017-05-02
200 OK2017-04-28
200 OK2017-04-25
200 OK2017-04-21
200 OK2017-04-18
200 OK2017-04-14
200 OK2017-04-11
200 OK2017-04-07
200 OK2017-04-04
200 OK2017-03-31
200 OK2017-03-28
200 OK2017-03-24
200 OK2017-03-21
200 OK2017-03-17
200 OK2017-03-14
200 OK2017-03-10
200 OK2017-03-07
200 OK2017-03-03
200 OK2017-02-28
200 OK2017-02-24
200 OK2017-02-21
200 OK2017-02-17
200 OK2017-02-14
200 OK2017-02-10
200 OK2017-02-07
200 OK2017-02-03
200 OK2017-01-31
200 OK2017-01-27
200 OK2017-01-24
200 OK2017-01-20
200 OK2017-01-17
200 OK2017-01-13
200 OK2017-01-10
200 OK2017-01-06
200 OK2017-01-03
200 OK2016-12-30
200 OK2016-12-27
200 OK2016-12-23
200 OK2016-12-20
200 OK2016-12-16
200 OK2016-12-13
200 OK2016-12-09
200 OK2016-12-06
200 OK2016-12-02
200 OK2016-11-29
200 OK2016-11-25
200 OK2016-11-22
200 OK2016-11-18
200 OK2016-11-15
200 OK2016-11-11
200 OK2016-11-08
200 OK2016-11-04
200 OK2016-11-01
200 OK2016-10-28
200 OK2016-10-25
200 OK2016-10-21
200 OK2016-10-18
200 OK2016-10-14
200 OK2016-10-11
200 OK2016-10-07
200 OK2016-10-04
200 OK2016-09-30
200 OK2016-09-27
200 OK2016-09-23
200 OK2016-09-20
200 OK2016-09-16
200 OK2016-09-13
200 OK2016-09-09
200 OK2016-09-06
200 OK2016-09-02
200 OK2016-08-30
200 OK2016-08-26
200 OK2016-08-23
200 OK2016-08-19
200 OK2016-08-16
200 OK2016-08-12
200 OK2016-08-09
200 OK2016-08-05
200 OK2016-08-02
200 OK2016-07-29
200 OK2016-07-26
200 OK2016-07-22
200 OK2016-07-19
200 OK2016-07-15
200 OK2016-07-12
200 OK2016-07-08
200 OK2016-07-05
200 OK2016-07-01
200 OK2016-06-28
200 OK2016-06-24
200 OK2016-06-21
200 OK2016-06-17
200 OK2016-06-14
200 OK2016-06-10
200 OK2016-06-07
200 OK2016-06-03
200 OK2016-05-31
200 OK2016-05-27
200 OK2016-05-24
200 OK2016-05-20
200 OK2016-05-17
200 OK2016-05-13
200 OK2016-05-10
200 OK2016-05-06
200 OK2016-05-03
200 OK2016-04-29
200 OK2016-04-26
200 OK2016-04-22
200 OK2016-04-19
200 OK2016-04-15
200 OK2016-04-12
200 OK2016-04-08
200 OK2016-04-05
200 OK2016-04-01
200 OK2016-03-29
200 OK2016-03-28
200 OK2016-03-25
200 OK2016-03-23
200 OK2016-03-21
200 OK2016-03-18
200 OK2016-03-16
200 OK2016-03-14
200 OK2016-03-11
200 OK2016-03-09
200 OK2016-03-07
200 OK2016-03-04
200 OK2016-03-02
200 OK2016-02-29
200 OK2016-02-26
200 OK2016-02-24
200 OK2016-02-22
200 OK2016-02-19
200 OK2016-02-17
200 OK2016-02-15
200 OK2016-02-14
200 OK2016-02-12
200 OK2016-02-10
200 OK2016-02-08
200 OK2016-02-07
200 OK2016-02-05
200 OK2016-02-03
200 OK2016-02-01
200 OK2016-01-31
200 OK2016-01-29
200 OK2016-01-27
200 OK2016-01-25
200 OK2016-01-24
200 OK2016-01-22
200 OK2016-01-20
200 OK2016-01-18
200 OK2016-01-17
200 OK2016-01-15
200 OK2016-01-13
200 OK2016-01-11
200 OK2016-01-10
200 OK2016-01-08
200 OK2016-01-06
200 OK2016-01-04


DNA Expression Interaction and Network Protein
Saccharomyces cerevisiae
gene information genomic information protein information

Record metadata

  • Created on: 2015-06-20
  • Curated by:
    • Shixiang Sun [2017-04-06]
    • Shixiang Sun [2017-03-24]
    • Shixiang Sun [2017-03-07]
    • Lin Xia [2016-03-28]
    • Mengwei Li [2016-02-19]
    • Lin Liu [2016-01-29]
    • Lin Liu [2016-01-05]
    • Lin Xia [2015-06-28]