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Database Commons - dbGaP

dbGaP

Citations: 85

z-index 7.44

Short name dbGaP
Full name Database of Genotypes and Phenotypes
Description dbGaP was developed to archive and distribute the results of studies that have investigated the interaction of genotype and phenotype.
URL http://www.ncbi.nlm.nih.gov/gap
Year founded 2014
Last update & version 2017-01-01    v1.4
Availability Free to all users
University/Institution hosted National Center for Biotechnology Information
Address Information Engineering Branch
City Bethesda
Province/State MD
Country/Region United States
Contact name Michael Feolo
Contact email feolo@ncbi.nlm.nih.gov
Data type(s)
Major organism(s)
Keyword(s)
  • interaction of genotype and phenotype
Publication(s)
  • The dbGaP data browser: a new tool for browsing dbGaP controlled-access genomic data. [PMID: 27899644]

    Kira M Wong, Kristofor Langlais, Geoffrey S Tobias, Colette Fletcher-Hoppe, Donna Krasnewich, Hilary S Leeds, Laura Lyman Rodriguez, Georgy Godynskiy, Valerie A Schneider, Erin M Ramos, Stephen T Sherry
    Nucleic acids research 2017:45(D1)
    0 Citations (Google Scholar as of 2017-02-20)

    Abstract: The database of Genotypes and Phenotypes (dbGaP) Data Browser (https://www.ncbi.nlm.nih.gov/gap/ddb/) was developed in response to requests from the scientific community for a resource that enable view-only access to summary-level information and individual-level genotype and sequence data associated with phenotypic features maintained in the controlled-access tier of dbGaP. Until now, the dbGaP controlled-access environment required investigators to submit a data access request, wait for Data Access Committee review, download each data set and locally examine them for potentially relevant information. Existing unrestricted-access genomic data browsing resources (e.g. http://evs.gs.washington.edu/EVS/, http://exac.broadinstitute.org/) provide only summary statistics or aggregate allele frequencies. The dbGaP Data Browser serves as a third solution, providing researchers with view-only access to a compilation of individual-level data from general research use (GRU) studies through a simplified controlled-access process. The National Institutes of Health (NIH) will continue to improve the Browser in response to user feedback and believes that this tool may decrease unnecessary download requests, while still facilitating responsible genomic data-sharing. Published by Oxford University Press on behalf of Nucleic Acids Research 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  • NCBI's Database of Genotypes and Phenotypes: dbGaP. [PMID: 24297256]

    Kimberly A Tryka, Luning Hao, Anne Sturcke, Yumi Jin, Zhen Y Wang, Lora Ziyabari, Moira Lee, Natalia Popova, Nataliya Sharopova, Masato Kimura, Michael Feolo
    Nucleic acids research 2014:42(Database issue)
    85 Citations (Google Scholar as of 2017-02-20)

    Abstract: The Database of Genotypes and Phenotypes (dbGap, http://www.ncbi.nlm.nih.gov/gap) is a National Institutes of Health-sponsored repository charged to archive, curate and distribute information produced by studies investigating the interaction of genotype and phenotype. Information in dbGaP is organized as a hierarchical structure and includes the accessioned objects, phenotypes (as variables and datasets), various molecular assay data (SNP and Expression Array data, Sequence and Epigenomic marks), analyses and documents. Publicly accessible metadata about submitted studies, summary level data, and documents related to studies can be accessed freely on the dbGaP website. Individual-level data are accessible via Controlled Access application to scientists across the globe.

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Accessibility

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200 OK2016-03-18
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200 OK2016-03-04
200 OK2016-03-02
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200 OK2016-02-19
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200 OK2016-02-15
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200 OK2016-01-29
200 OK2016-01-27
200 OK2016-01-25
200 OK2016-01-24
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200 OK2016-01-17
200 OK2016-01-15
200 OK2016-01-13
200 OK2016-01-11
200 OK2016-01-10
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200 OK2016-01-04

Tags

DNA Phenotype
Homo sapiens
interaction of genotype and phenotype

Record metadata

  • Created on: 2015-06-20
  • Curated by:
    • Shixiang Sun [2017-02-20]
    • Lina Ma [2016-04-13]
    • Jian Sang [2016-04-04]
    • Mengwei Li [2016-02-13]
    • Lina Ma [2015-11-25]
    • Zhang Zhang [2015-06-27]
    • Jian Sang [2015-06-26]
Stats