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Database Commons - METscout

METscout

Citations: 2

z-index 0.40

Short name METscout
Full name METscout
Description The METscout relational database brings together metabolism and gene expression landscapes. Biochemistry textbooks and more recently digital resources such as KEGG (Kyoto Encyclopedia of Genes and Genomes) represent metabolism in two-dimensional charts in which a wealth of metabolites and metabolic enzymes form an integrated metabolic network.
URL http://metscout.mpg.de/
Year founded 2012
Last update & version 2014-5-5    v1.0
Availability Free to all users
University/Institution hosted Max Planck Institute for Biophysical Chemistry
Address Göttingen, Germany
City Göttingen
Province/State
Country/Region Germany
Contact name Gregor Eichele
Contact email geichel@gwdg.de
Data type(s)
Major organism(s)
Keyword(s)
  • metabolic enzyme
  • metabolite
Publication(s)
  • METscout: a pathfinder exploring the landscape of metabolites, enzymes and transporters. [PMID: 23019219]

    Lars Geffers, Benjamin Tetzlaff, Xiao Cui, Jun Yan, Gregor Eichele
    Nucleic acids research 2013:41(Database issue)
    2 Citations (Google Scholar as of 2016-02-29)

    Abstract: METscout (http://metscout.mpg.de) brings together metabolism and gene expression landscapes. It is a MySQL relational database linking biochemical pathway information with 3D patterns of gene expression determined by robotic in situ hybridization in the E14.5 mouse embryo. The sites of expression of ?1500 metabolic enzymes and of ?350 solute carriers (SLCs) were included and are accessible as single cell resolution images and in the form of semi-quantitative image abstractions. METscout provides several graphical web-interfaces allowing navigation through complex anatomical and metabolic information. Specifically, the database shows where in the organism each of the many metabolic reactions take place and where SLCs transport metabolites. To link enzymatic reactions and transport, the KEGG metabolic reaction network was extended to include metabolite transport. This network in conjunction with spatial expression pattern of the network genes allows for a tracing of metabolic reactions and transport processes across the entire body of the embryo.

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Accessibility

Rate of accessibility:
HTTP status codeDate requested
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200 OK2017-03-14
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200 OK2017-03-07
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200 OK2016-10-18
200 OK2016-10-14
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200 OK2016-09-27
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200 OK2016-02-22
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200 OK2016-02-15
200 OK2016-02-14
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200 OK2016-02-08
200 OK2016-02-07
200 OK2016-02-05
200 OK2016-02-03
200 OK2016-02-01
200 OK2016-01-31
200 OK2016-01-29
200 OK2016-01-27
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200 OK2016-01-22
200 OK2016-01-20
200 OK2016-01-18
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200 OK2016-01-15
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200 OK2016-01-08
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200 OK2016-01-04

Tags

Expression Interaction and Network Metabolic and Signaling Pathway
metabolic enzyme metabolite

Record metadata

  • Created on: 2015-06-20
  • Curated by:
    • Lin Liu [2016-03-29]
    • Lin Liu [2016-03-26]
    • Lina Ma [2015-11-26]
    • Li Yang [2015-11-23]
    • Li Yang [2015-06-26]
Stats