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Database Commons - PhEVER

PhEVER

Citations: 4

z-index 0.06

Short name PhEVER
Full name phylogenetic exploration of virues' evolutionary relationships
Description PhEVER is a database of homologous gene families providing information for the understanding of virus/host co-evolution. Each family supplies pre-computed alignment and phylogeny
URL http://pbil.univ-lyon1.fr/databases/phever
Year founded 2010
Last update & version 2011-01-01    v1.0
Availability Free to all users
University/Institution hosted French National Centre for Scientific Research
Address F-69622, Villeurbanne, France
City Villeurbanne
Province/State
Country/Region France
Contact name Leonor Palmeira
Contact email mlpalmeira@ulg.ac.be
Data type(s)
Major organism(s)
Keyword(s)
  • homologous family
  • lateral gene transfer
  • virus/host co-evolution
Publication(s)
  • PhEVER: a database for the global exploration of virus-host evolutionary relationships. [PMID: 21081560]

    Leonor Palmeira, Simon Penel, Vincent Lotteau, Chantal Rabourdin-Combe, Christian Gautier
    Nucleic acids research 2011:39(Database issue)
    4 Citations (Google Scholar as of 2016-04-28)

    Abstract: Fast viral adaptation and the implication of this rapid evolution in the emergence of several new infectious diseases have turned this issue into a major challenge for various research domains. Indeed, viruses are involved in the development of a wide range of pathologies and understanding how viruses and host cells interact in the context of adaptation remains an open question. In order to provide insights into the complex interactions between viruses and their host organisms and namely in the acquisition of novel functions through exchanges of genetic material, we developed the PhEVER database. This database aims at providing accurate evolutionary and phylogenetic information to analyse the nature of virus-virus and virus-host lateral gene transfers. PhEVER (http://pbil.univ-lyon1.fr/databases/phever) is a unique database of homologous families both (i) between sequences from different viruses and (ii) between viral sequences and sequences from cellular organisms. PhEVER integrates extensive data from up-to-date completely sequenced genomes (2426 non-redundant viral genomes, 1007 non-redundant prokaryotic genomes, 43 eukaryotic genomes ranging from plants to vertebrates) and offers a clustering of proteins into homologous families containing at least one viral sequences, as well as alignments and phylogenies for each of these families. Public access to PhEVER is available through its webpage and through all dedicated ACNUC retrieval systems.

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Tags

DNA
Eukaryota Prokaryote Virus
homologous family lateral gene transfer virus/host co-evolution

Record metadata

  • Created on: 2015-06-20
  • Curated by:
    • Shixiang Sun [2016-03-28]
    • Shixiang Sun [2016-03-25]
    • Shixiang Sun [2015-11-21]
    • Shixiang Sun [2015-06-28]
    • Shixiang Sun [2015-06-26]
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