Database Commons a catalog of biological databases

Database Commons - ProteomeScout

ProteomeScout

Citations: 0

z-index 0.00

Short name ProteomeScout
Full name
Description ProteomeScout is a database of proteins and post-translational modifications.
URL https://proteomescout.wustl.edu/
Year founded 2014
Last update & version 2015-03-01    v2.0
Availability Free to all users
University/Institution hosted Washington University
Address St Louis, Missouri 63130,USA
City St Louis
Province/State Missouri
Country/Region United States
Contact name Kristen M. Naegle
Contact email knaegle@wustl.edu
Data type(s)
Major organism(s)
Keyword(s)
  • post-translational modification
Publication(s)
  • ProteomeScout: a repository and analysis resource for post-translational modifications and proteins. [PMID: 25414335]

    Matthew K Matlock, Alex S Holehouse, Kristen M Naegle
    Nucleic acids research 2015:43(Database issue)
    Citation (to be updated)

    Abstract: ProteomeScout (https://proteomescout.wustl.edu) is a resource for the study of proteins and their post-translational modifications (PTMs) consisting of a database of PTMs, a repository for experimental data, an analysis suite for PTM experiments, and a tool for visualizing the relationships between complex protein annotations. The PTM database is a compendium of public PTM data, coupled with user-uploaded experimental data. ProteomeScout provides analysis tools for experimental datasets, including summary views and subset selection, which can identify relationships within subsets of data by testing for statistically significant enrichment of protein annotations. Protein annotations are incorporated in the ProteomeScout database from external resources and include terms such as Gene Ontology annotations, domains, secondary structure and non-synonymous polymorphisms. These annotations are available in the database download, in the analysis tools and in the protein viewer. The protein viewer allows for the simultaneous visualization of annotations in an interactive web graphic, which can be exported in Scalable Vector Graphics (SVG) format. Finally, quantitative data measurements associated with public experiments are also easily viewable within protein records, allowing researchers to see how PTMs change across different contexts. ProteomeScout should prove useful for protein researchers and should benefit the proteomics community by providing a stable repository for PTM experiments. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

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Tags

Protein
Eukaryota Prokaryote
post-translational modification

Record metadata

  • Created on: 2015-06-20
  • Curated by:
    • Shixiang Sun [2016-03-28]
    • Shixiang Sun [2015-11-22]
    • Shixiang Sun [2015-06-28]
    • Shixiang Sun [2015-06-26]
Stats