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Database Commons - BGDB

BGDB

Citations: 4

z-index 0.04

Short name BGDB
Full name Bivalent Genes Database
Description BGDB database contains 3,913 bivalent genes in human ES cells and 2,984 genes in mouse.
URL http://dailab.sysu.edu.cn/bgdb/
Year founded 2013
Last update & version NA    v1.0
Availability Free to all users
University/Institution hosted Sun Yat-Sen University
Address Guangzhou 510006,China
City Guangzhou
Province/State Guangdong
Country/Region China
Contact name Xianhua Dai
Contact email issdxh@mail.sysu.edu.cn
Data type(s)
Major organism(s)
Keyword(s)
  • bivalent gene
  • H3K27me3
  • H3K4me3
Publication(s)
  • BGDB: a database of bivalent genes. [PMID: 23894186]

    Qingyan Li, Shuabin Lian, Zhiming Dai, Qian Xiang, Xianhua Dai
    Database : the journal of biological databases and curation 2013:2013
    4 Citations (Google Scholar as of 2016-01-29)

    Abstract: Bivalent gene is a gene marked with both H3K4me3 and H3K27me3 epigenetic modification in the same area, and is proposed to play a pivotal role related to pluripotency in embryonic stem (ES) cells. Identification of these bivalent genes and understanding their functions are important for further research of lineage specification and embryo development. So far, lots of genome-wide histone modification data were generated in mouse and human ES cells. These valuable data make it possible to identify bivalent genes, but no comprehensive data repositories or analysis tools are available for bivalent genes currently. In this work, we develop BGDB, the database of bivalent genes. The database contains 6897 bivalent genes in human and mouse ES cells, which are manually collected from scientific literature. Each entry contains curated information, including genomic context, sequences, gene ontology and other relevant information. The web services of BGDB database were implemented with PHP + MySQL + JavaScript, and provide diverse query functions. Database URL: http://dailab.sysu.edu.cn/bgdb/

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Tags

DNA Modification
Homo sapiens Mus musculus
bivalent gene H3K27me3 H3K4me3

Record metadata

  • Created on: 2015-06-20
  • Curated by:
    • Mengwei Li [2015-06-26]
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