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Database Commons - CHD@ZJU

CHD@ZJU

Citations: 7

z-index 0.69

Short name CHD@ZJU
Full name Coronary Heart Disease Research Platform
Description Coronary Heart Disease @ZJU (CHD@ZJU) is a curated knowledge-base to provide a network based study platform on coronary heart disease.
URL http://tcm.zju.edu.cn/chd/
Year founded 2013
Last update & version NA    v2.0
Availability Free to all users
University/Institution hosted Zhejiang University
Address Hangzhou 310058,China
City Hangzhou
Province/State Zhejiang
Country/Region China
Contact name Yiyu Cheng
Contact email fanxh@zju.edu.cn
Data type(s)
Major organism(s)
Keyword(s)
  • CHD
  • coronary heart disease
Publication(s)
  • CHD@ZJU: a knowledgebase providing network-based research platform on coronary heart disease. [PMID: 23818526]

    Leihong Wu, Xiang Li, Jihong Yang, Yufeng Liu, Xiaohui Fan, Yiyu Cheng
    Database : the journal of biological databases and curation 2013:2013
    7 Citations (Google Scholar as of 2016-02-28)

    Abstract: Coronary heart disease (CHD), the leading cause of global morbidity and mortality in adults, has been reported to be associated with hundreds of genes. A comprehensive understanding of the CHD-related genes and their corresponding interactions is essential to advance the translational research on CHD. Accordingly, we construct this knowledgebase, CHD@ZJU, which records CHD-related information (genes, pathways, drugs and references) collected from different resources and through text-mining method followed by manual confirmation. In current release, CHD@ZJU contains 660 CHD-related genes, 45 common pathways and 1405 drugs accompanied with >8000 supporting references. Almost half of the genes collected in CHD@ZJU were novel to other publicly available CHD databases. Additionally, CHD@ZJU incorporated the protein-protein interactions to investigate the cross-talk within the pathways from a multi-layer network view. These functions offered by CHD@ZJU would allow researchers to dissect the molecular mechanism of CHD in a systematic manner and therefore facilitate the research on CHD-related multi-target therapeutic discovery. Database URL: http://tcm.zju.edu.cn/chd/

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Tags

Disease DNA Interaction and Network Metabolic and Signaling Pathway
Homo sapiens
CHD coronary heart disease

Record metadata

  • Created on: 2015-06-20
  • Curated by:
    • Mengwei Li [2016-03-31]
    • Mengwei Li [2015-12-02]
    • Mengwei Li [2015-06-27]
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