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Database Commons - miRBase Tracker

miRBase Tracker

Citations: 14

z-index 3.29

Short name miRBase Tracker
Full name miRBase Tracker
Description Keeping track of microRNA annotation changes.
URL http://www.mirbasetracker.org/
Year founded 2014
Last update & version 2014-08-24    v1.0
Availability Free to all users
University/Institution hosted Ghent University
Address Ghent, Belgium
City Ghent
Province/State
Country/Region Belgium
Contact name Jo Vandesompele
Contact email joke.vandesompele@ugent.be
Data type(s)
Major organism(s)
Keyword(s)
  • miRBase
  • miRNA annotation
Publication(s)
  • miRBase Tracker: keeping track of microRNA annotation changes. [PMID: 25157074]

    Gert Van Peer, Steve Lefever, Jasper Anckaert, Anneleen Beckers, Ali Rihani, Alan Van Goethem, Pieter-Jan Volders, Fjoralba Zeka, Maté Ongenaert, Pieter Mestdagh, Jo Vandesompele
    Database : the journal of biological databases and curation 2014:2014
    14 Citations (Google Scholar as of 2016-03-03)

    Abstract: Since 2002, information on individual microRNAs (miRNAs), such as reference names and sequences, has been stored in miRBase, the reference database for miRNA annotation. As a result of progressive insights into the miRNome and its complexity, miRBase underwent addition and deletion of miRNA records, changes in annotated miRNA sequences and adoption of more complex naming schemes over time. Unfortunately, miRBase does not allow straightforward assessment of these ongoing miRNA annotation changes, which has resulted in substantial ambiguity regarding miRNA identity and sequence in public literature, in target prediction databases and in content on various commercially available analytical platforms. As a result, correct interpretation, comparison and integration of miRNA study results are compromised, which we demonstrate here by assessing the impact of ignoring sequence annotation changes. To address this problem, we developed miRBase Tracker (www.mirbasetracker.org), an easy-to-use online database that keeps track of all historical and current miRNA annotation present in the miRBase database. Three basic functionalities allow researchers to keep their miRNA annotation up-to-date, reannotate analytical miRNA platforms and link published results with outdated annotation to the latest miRBase release. We expect miRBase Tracker to increase the transparency and annotation accuracy in the field of miRNA research. www.mirbasetracker.org. © The Author(s) 2014. Published by Oxford University Press.

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200 OK2016-01-15
200 OK2016-01-13
200 OK2016-01-11
200 OK2016-01-10
200 OK2016-01-08
200 OK2016-01-06
200 OK2016-01-04

Tags

RNA
Caenorhabditis elegans Danio rerio Drosophila melanogaster Homo sapiens Mus musculus Rattus norvegicus
miRBase miRNA annotation

Record metadata

  • Created on: 2015-06-20
  • Curated by:
    • Lin Liu [2016-03-29]
    • Li Yang [2015-06-26]
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