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Database Commons - EpimiR

EpimiR

Citations: 8

z-index 1.50

Short name EpimiR
Full name Database of Curated Mutual Regulation Between epigenetic Modifications and miRNAs
Description The EpimiR database have obtained 1974 regulatory relationships between 19 types of epigenetic modifications (including DNA methylation, histone acetylation, H3K4me3 and H3K27me3, etc.) and 617 miRNAs across 7 species (including Homo sapiens, Mus musculus, Rattus norvegicus, Gallus gallus, Epstein Barr virus, Canis familiaris and Arabidopsis thaliana) from nearly 2000 literatures.
URL http://210.46.85.180:8080/EpimiR/
Year founded 2014
Last update & version NA    v1.0
Availability Free to all users
University/Institution hosted Harbin Medical University
Address Harbin 150081, China
City Harbin
Province/State Heilongjiang
Country/Region China
Contact name Wei Jiang
Contact email angwei@hrbmu.edu.cn
Data type(s)
Major organism(s)
Keyword(s)
  • epigenetic modification
  • miRNA
Publication(s)
  • EpimiR: a database of curated mutual regulation between miRNAs and epigenetic modifications. [PMID: 24682734]

    Enyu Dai, Xuexin Yu, Yan Zhang, Fanlin Meng, Shuyuan Wang, Xinyi Liu, Dianming Liu, Jing Wang, Xia Li, Wei Jiang
    Database : the journal of biological databases and curation 2014:2014
    8 Citations (Google Scholar as of 2016-04-28)

    Abstract: As two kinds of important gene expression regulators, both epigenetic modification and microRNA (miRNA) can play significant roles in a wide range of human diseases. Recently, many studies have demonstrated that epigenetics and miRNA can affect each other in various ways. In this study, we established the EpimiR database, which collects 1974 regulations between 19 kinds of epigenetic modifications (such as DNA methylation, histone acetylation, H3K4me3, H3S10p) and 617 miRNAs across seven species (including Homo sapiens, Mus musculus, Rattus norvegicus, Gallus gallus, Epstein-Barr virus, Canis familiaris and Arabidopsis thaliana) from >300 references in the literature. These regulations can be divided into two parts: miR2Epi (103 entries describing how miRNA regulates epigenetic modification) and Epi2miR (1871 entries describing how epigenetic modification affects miRNA). Each entry of EpimiR not only contains basic descriptions of the validated experiment (method, species, reference and so on) but also clearly illuminates the regulatory pathway between epigenetics and miRNA. As a supplement to the curated information, the EpimiR extends to gather predicted epigenetic features (such as predicted transcription start site, upstream CpG island) associated with miRNA for users to guide their future biological experiments. Finally, EpimiR offers download and submission pages. Thus, EpimiR provides a fairly comprehensive repository about the mutual regulation between epigenetic modifications and miRNAs, which will promote the research on the regulatory mechanism of epigenetics and miRNA. Database URL: http://bioinfo.hrbmu.edu.cn/EpimiR/.

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Accessibility

Rate of accessibility:
HTTP status codeDate requested
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200 OK2018-04-06
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200 OK2018-02-27
200 OK2018-02-23
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200 OK2018-02-16
200 OK2018-02-13
200 OK2018-02-09
200 OK2018-02-06
200 OK2018-02-02
200 OK2018-01-30
200 OK2018-01-26
200 OK2018-01-23
200 OK2018-01-19
200 OK2018-01-16
200 OK2018-01-12
200 OK2018-01-09
200 OK2018-01-05
200 OK2018-01-02
200 OK2017-12-29
200 OK2017-12-26
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200 OK2017-12-01
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200 OK2017-11-10
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200 OK2017-05-09
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200 OK2017-04-14
200 OK2017-04-11
200 OK2017-04-07
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200 OK2017-03-14
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200 OK2017-03-07
200 OK2017-03-03
200 OK2017-02-28
200 OK2017-02-24
200 OK2017-02-21
200 OK2017-02-17
200 OK2017-02-14
200 OK2017-02-10
200 OK2017-02-07
200 OK2017-02-03
200 OK2017-01-31
200 OK2017-01-27
200 OK2017-01-24
200 OK2017-01-20
200 OK2017-01-17
200 OK2017-01-13
200 OK2017-01-10
200 OK2017-01-06
200 OK2017-01-03
200 OK2016-12-30
200 OK2016-12-27
200 OK2016-12-23
200 OK2016-12-20
200 OK2016-12-16
200 OK2016-12-13
200 OK2016-12-09
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200 OK2016-12-02
200 OK2016-11-29
200 OK2016-11-25
200 OK2016-11-22
200 OK2016-11-18
200 OK2016-11-15
200 OK2016-11-11
200 OK2016-11-08
200 OK2016-11-04
200 OK2016-11-01
200 OK2016-10-28
200 OK2016-10-25
200 OK2016-10-21
200 OK2016-10-18
200 OK2016-10-14
200 OK2016-10-11
200 OK2016-10-07
200 OK2016-10-04
200 OK2016-09-30
200 OK2016-09-27
200 OK2016-09-23
200 OK2016-09-20
200 OK2016-09-16
200 OK2016-09-13
200 OK2016-09-09
200 OK2016-09-06
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200 OK2016-08-30
200 OK2016-08-26
200 OK2016-08-23
200 OK2016-08-19
200 OK2016-08-16
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200 OK2016-08-09
200 OK2016-08-05
200 OK2016-08-02
200 OK2016-07-29
200 OK2016-07-26
200 OK2016-07-22
200 OK2016-07-19
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200 OK2016-07-08
200 OK2016-07-05
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200 OK2016-06-21
200 OK2016-06-17
200 OK2016-06-14
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200 OK2016-06-07
200 OK2016-06-03
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Tags

DNA Modification RNA
Arabidopsis thaliana Canis familiaris Epsteinðbarr virus Gallus gallus Homo sapiens Mus musculus Rattus norvegicus
epigenetic modification miRNA

Record metadata

  • Created on: 2015-06-20
  • Curated by:
    • Lina Ma [2016-10-14]
    • Jian Sang [2016-04-05]
    • Jian Sang [2015-12-11]
    • Jian Sang [2015-06-27]
Stats